Arsenal head to Newcastle on the last day of the season in fourth place, just a point above arch rivals Tottenham.
A Gunners win will secure a top four finish and a Champions League spot. Tottenham host Sunderland at White Hart Lane and know nothing but a win is good enough to secure a top four spot.
If Arsenal wins then even a win would not give them a top four finish and Spurs would have to settle for a place in the Europa League next season.
Elsewhere, veteran Manchester United boss Sir Alex Ferguson is in charge of his last game as United boss after more than 26 years in charge, as his team visits midtable West Brom. It is likely to be an emotional day for the Scot, who will be replaced this summer by compatriot David Moyes.
Moyes himself will be bidding farewell to Everton, after 11 years in charge at Goodison, as the Toffees face Chelsea at Stamford Bridge. Moyes has helped the Toffees to sixth place this season and their second consecutive finish above city rivals Liverpool.
The home side are yet to confirm third place, but could do with a draw or a win. A 0-0 draw combined with a 2-1 win for Arsenal would mean a play-off between the two teams for third spot.
The game will be Rafa Benitez’s last in charge of Chelsea, with Jose Mourinho believed to be ready to return to the Bridge this summer.
Other Premier League fixtures:
Liverpool vs. QPR
Manchester City vs. Norwich
Southampton vs. Stoke
Swansea vs. Fulham
West Ham vs. Reading
Wigan vs. Aston Villa
Who will finish in fourth place in the Premier League?
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It's been great seeing Messi and Neymar play together. Hopefully they'
Genius starts with "G" and finishes with "S"...................... So
Lets hope these two greats of the game get a chance to play to gather.
hi. a lot of football expertss expected west bromwich albion to go dow
RVP are you being serious?? A blip in leauge form and a poor finish fo