Saturday’s Premier League games could have great significance at both ends of the table.

At St Marys Southampton host QPR looking to move further away from the relegation zone.

The home side are still just three points away from the drop zone and are in desperate need of maximum points.

The visitors meanwhile are seven points away from safety and have to start winning games. The Hoops have claimed just two victories in the league this season. If they are to survive the comeback needs to start in tomorrow’s game.

Elsewhere, Everton will be looking to cut the gap between themselves and fourth place Tottenham to four points, as the Toffees host struggling Reading at Goodison Park. Wins have been hard to come by for David Moyes’ Toffees in recent weeks, but they did beat Oldham in the FA Cup in midweek to make it into the quarter-finals.

The visitors are second from bottom in the Premier League, but are just a point from safety. An unlikely away win at Goodison Park could move the Royals out of the relegation zone. However, it will be a difficult task, as Everton have an excellent home record.

Elsewhere, Manchester United host Norwich looking to extend their lead over arch-rivals Manchester City at the top of the table. The Red Devils are currently 12 points clear of their city rivals, who play tomorrow.

Star striker Robin van Persie has recovered from a slight knock and is expected to take some part in the game, although he may be rested with United facing Real Madrid in the Champions League on Tuesday night.

The visitors claimed a late 2-1 victory over Everton in their last outing, but the trip to Old Trafford is a far different clash all together. The Canaries are currently eight points clear of the relegation zone, but will be looking over their shoulders.

Other Premier League games on Saturday:

Chelsea vs. West Brom

Stoke vs. West Ham

Sunderland vs. Fulham

Swansea vs. Newcastle

Wigan vs. Liverpool

Who will occupy the relegation places at the end of tomorrow’s action?